Service
Breakthrough Relief When Traditional Antidepressants Haven’t Worked
FDA-approved esketamine nasal spray offering rapid relief for treatment-resistant depression, PTSD, and suicidal ideation. At Resilience Integrative Wellness, we’re proud to be a REMS-certified provider of Spravato treatment, bringing hope to patients when conventional approaches have fallen short.
Covered By Insurance
Rapid Results Within Hours
Serving San Diego at 6719 Alvarado Road, Suite 201
Spravato represents a groundbreaking advancement in mental health treatment, offering new hope for individuals struggling with treatment-resistant depression. As the brand name for esketamine, Spravato is the first and only FDA-approved nasal spray specifically designed to treat adults with treatment-resistant depression, major depressive disorder with suicidal ideation, and certain cases of PTSD when co-occurring with depression.
Unlike traditional antidepressants that can take weeks or months to show effects, Spravato works through a completely different mechanism. While conventional medications target serotonin or dopamine pathways, Spravato acts on the brain’s glutamate system, allowing for rapid relief that can begin within hours of your first treatment.
What makes Spravato particularly valuable is its FDA approval status, which means it’s often covered by insurance for qualifying patients. This makes innovative mental health treatment more accessible than ever before for those who need it most.
Speed of Relief
Spravato
Hours to days
4-8 weeks or longer
Success Rate
Spravato
70% remission rate in clinical trials
Traditional Antidepressants
Lower rates for treatment-resistant cases
Insurance Coverage
Spravato
Often covered for approved indications
Traditional Antidepressants
Typically covered but limited effectiveness
Mechanism
Spravato
Traditional Antidepressants
Serotonin/dopamine systems
Side Effects
Spravato
Temporary, resolve within hours
Traditional Antidepressants
Often persistent and ongoing
Administration
Spravato
Supervised nasal spray in clinic
Traditional Antidepressants
Self-administered daily pills
Schedule
Mon – Fri (9:30 AM to 6:00 PM)
Saturday (By Appointment)
Sunday (Closed)
Location
6719 Alvarado Road, Suite 201 San Diego, CA 92120
Compassionate ketamine therapy designed for those who haven’t found relief through traditional treatments.
When you’ve tried two or more antidepressants without adequate relief, Spravato offers new hope. Learn more about depression treatment in San Diego
When PTSD occurs alongside treatment-resistant depression, Spravato may offer relief for both conditions. Learn more about PTSD treatment in San Diego
In certain cases, Spravato may be beneficial for the depressive episodes of bipolar disorder. Learn more about bipolar disorder treatment in San Diego
The revolutionary effectiveness of Spravato comes from its unique approach to treating depression. Traditional antidepressants work by targeting serotonin or dopamine neurotransmitters and typically require 4-6 weeks before any measurable improvement occurs. Spravato takes a completely different approach.
Spravato acts on glutamate, the brain’s primary excitatory neurotransmitter and the most abundant neurotransmitter in the central nervous system. By blocking NMDA receptors, Spravato triggers a cascade of neurobiological changes that promote neuroplasticity – the brain’s ability to form new neural connections and pathways.
This neuroplasticity allows your brain to essentially “rewire” itself, breaking free from the dysfunctional patterns associated with depression. The process promotes the growth of new, healthy neural connections, which contributes to improved mood regulation and enhanced emotional resilience.
The self-administered nasal spray delivery system ensures the medication is absorbed quickly through the nasal tissues, allowing for rapid onset of therapeutic effects. This innovative delivery method makes treatment more convenient while maintaining the controlled medical environment required for safety.
Your Spravato journey begins with a thorough evaluation by our medical team. We’ll review your detailed medical history, previous antidepressant trials, and current symptoms to determine if you’re a candidate for Spravato treatment. During this consultation, we’ll also verify your insurance benefits and discuss the prior authorization process if needed.
We’ll explain the entire treatment process, answer all your questions, and ensure you understand what to expect during each phase of treatment. This consultation is complimentary and comes with no obligation to proceed with treatment.
Spravato follows a structured, FDA-approved treatment schedule designed to maximize effectiveness:
Induction Phase (Weeks 1-4) During your first month, you’ll receive Spravato treatments twice weekly. This intensive initial phase helps establish therapeutic levels and begin the neuroplastic changes that lead to symptom improvement.
Maintenance Phase (Weeks 5-8) In the second month, treatment frequency reduces to once weekly as your symptoms improve and stabilize. This phase allows your brain to consolidate the positive changes while maintaining therapeutic momentum.
Continuation Phase (Week 9 and beyond) After the first two months, treatments typically occur once weekly or once every two weeks, based on your individual response and needs. Some patients benefit from continued maintenance treatment for extended periods to sustain their improvement.
On treatment days, you’ll arrive at our comfortable San Diego clinic where our medical team will guide you through the self-administration process. The Spravato nasal spray device is simple to use, and our staff will ensure you’re completely comfortable with the process.
After self-administering your Spravato dose, you’ll relax in one of our private treatment rooms equipped with luxury amenities including reclining chairs, soft blankets, and Bose headphones. Our medical team will continuously monitor your vital signs and ensure your comfort throughout the required monitoring period of at least two hours.
It’s important to arrange transportation for treatment days, as you cannot drive or operate machinery until the next day after receiving Spravato.
We are an authorized REMS-certified facility, meeting all FDA requirements for safe Spravato administration. This certification ensures the highest standards of care and safety protocols.
Our clinical team brings over 60 years of combined medical experience, with specialized training in innovative mental health treatments and trauma-informed care.
Our six private treatment rooms feature luxury amenities including reclining chairs, Bose headphones, soft blankets, and complimentary refreshments to ensure your comfort during monitoring periods.
We integrate Spravato treatment with other innovative therapies and work closely with your existing mental health providers for coordinated, holistic care.
As a veteran-owned practice, we have a deep understanding of trauma, PTSD, and the unique mental health challenges faced by service members and their families.
Our team has extensive experience navigating prior authorization processes and maximizing insurance benefits for innovative mental health treatments.
STEP 1
Spravato is the only FDA-approved nasal spray specifically for treatment-resistant depression, backed by extensive clinical trials demonstrating its safety and effectiveness.
Unlike many innovative mental health treatments, Spravato is often covered by insurance for qualifying patients with treatment-resistant depression, making breakthrough care more accessible.
STEP 3
Many patients experience significant improvement within hours rather than the weeks or months typically required by traditional antidepressants.
STEP 4
The simple nasal spray format eliminates the need for IV insertion while maintaining the effectiveness of ketamine-based therapy.
What to bring to your consultation:
Current medication list
Don’t let treatment-resistant mental health conditions or chronic pain control your life any longer. At Resilience Integrative Wellness, we’re here to help you find the breakthrough relief you’ve been searching for.
Spravato has been extensively studied and has a well-established safety profile when administered in appropriate medical settings. As part of the FDA’s Risk Evaluation and Mitigation Strategy (REMS) program, Spravato can only be administered in certified healthcare facilities by trained providers.
Increased blood pressure
Uncontrolled high blood pressure
Pregnancy or breastfeeding
Certain heart conditions
During your consultation, our medical team will thoroughly review your health history to determine if Spravato treatment is safe and appropriate for you.
Most major insurance plans cover Spravato for FDA-approved indications like treatment-resistant depression. Coverage typically requires prior authorization and documentation of previous treatment failures. Our team will help verify your specific benefits and guide you through the approval process.
No, you cannot drive or operate machinery until the next day after receiving Spravato. You must arrange for someone to drive you home after each treatment session. This is a safety requirement due to the medication’s effects.
The typical protocol includes twice-weekly treatments for the first month, weekly treatments in the second month, and then weekly or bi-weekly maintenance treatments based on your response. Your specific schedule will be customized to your needs.
Common temporary side effects include dissociation, dizziness, nausea, fatigue, and headache. These effects typically resolve within 1-2 hours and are closely monitored by our medical team throughout your treatment.
Spravato is FDA-approved specifically for treatment-resistant depression and is often covered by insurance, while ketamine infusions are used off-label and typically aren’t covered. Spravato is self-administered as a nasal spray, while ketamine requires IV infusion.
No, Spravato is designed to be used alongside an oral antidepressant. You should continue your current medications unless specifically directed otherwise by your healthcare provider.
If you don’t respond adequately to Spravato, we can explore other innovative treatment options including ketamine infusions or TMS therapy. We’ll work with you to find the most effective approach for your specific situation.
Customized vitamin and nutrient infusions to support overall wellness and recovery. Learn more about IV therapy in San Diego
