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Whether you have general questions about ketamine and other psychedelic therapies or are interested in scheduling a complimentary consultation, we look forward to connecting with you.

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Ketamine to Treat Depression

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What Is Ketamine?

Ketamine is a medication frequently employed as an anesthetic, typically in outpatient care or emergency departments, because of its exceptional safety record.

Ketamine treatment, also known as ketamine therapy or ketamine psychedelics, involves the use of this medication to alleviate symptoms of conditions that are often resistant to traditional treatments, like depression or thoughts of self-harm.

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Imagine feeling relief from your depression symptoms within hours instead of weeks or months. With help from ketamine infusions for depression, recovery is possible and within reach.

If you have an aversion to needles, you can still get on the road to wellness, thanks to SPRAVATO®. An innovative nasal spray, it provides rapid relief and is a testament to the transformative, fast-acting power of ketamine. Schedule a complimentary consultation to learn more about how ketamine treatments can help you take back control.

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Why It’s a Preferred Treatment


Having been used for decades, ketamine is trusted within the medical profession and is backed by an outstanding safety record.


It’s very successful in alleviating pain and improving mood, as treatment targets brain receptors responsible for those feelings.


Ketamine is FDA-approved and a legal psychedelic when administered by registered medical practitioners like those on our staff.


Because ketamine is typically delivered intravenously or by intramuscular injection, it’s incredibly fast-acting, often working within hours.

Ketamine vs. Traditional Treatments

The legal psychedelic ketamine affects a range of neurotransmitters and neural pathways. That fact alone helps improve mood more quickly than conventional antidepressant treatments, as those only target specific neurotransmitters, like serotonin.

Ketamine for depression also has a lower risk of side effects compared to traditional treatments. It's well-tolerated, allowing many to bypass the side effects of traditional antidepressants, like sexual dysfunction, drowsiness, and weight gain. If you or someone you know is looking for an alternative depression treatment in San Diego, CA, reach out to our Resilience Integrative Wellness team to learn more about ketamine, psychedelics, and our individualized approach.

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Of study participants experienced significant improvements in life/work functionality


Of study participants saw improvements in depression symptoms


Of study participants with treatment-resistant depression reported reduced symptoms after repeated ketamine infusions

How Does Ketamine Treat Depression?

Ketamine is thought to boost the activity of glutamate, a neurotransmitter involved in the formation of new nerve cell connections in the brain. This process, called synaptic plasticity, is believed to be vital for learning, memory, and the ability to adapt to new situations. By increasing synaptic plasticity, ketamine may actually help the brain rewire itself to overcome negative patterns.

Ketamine may also impact the body's stress response system, which is vital in regulating mood. People suffering from depression have an overactive stress response system, leading to chronic feelings of pain, sadness, and hopelessness. Through infusions, ketamine works to stabilize that response system, improving mood.

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Ketamine for Depression FAQs


Experience a state of exhilarating consciousness that’s powered by your own voice. SoundSelf mixes breath and voice work concepts to bring about a relaxing, meditative-like state. Trusted by a wide network of professionals, it’s yet another revolutionary way we can help improve your mental health.

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Your Wellness Allies

Our dedicated professionals, who collectively have over 60 years of experience in medicine, are at the heart of our practice. Because of these expert clinicians, we offer an environment where clients feel heard, valued, and empowered in their recovery journey. Meet our team members today, the ones who prioritize safe, healing experiences.

Meet the Team
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Our Partners, Your Network

We're not just a ketamine clinic – we're a healthcare team with a holistic approach dedicated to helping you live life pain-free. As part of our approach, we offer a partner network comprised of other therapists in the area who provide beneficial services. We're here for you, whether or not you use our treatments.

Joy Wellness Partners
Affirming Therapy Center
ABCounseling, Inc.
Genelle Weits Garcia, Ph.D

Over 20 years of expertise in treating chronic pain and the many challenges that come with it, including identity changes, grief & loss, depression, and anxiety.

(619) 268-1081


Psychology Today Profile



Visit our blog to learn more about ketamine, psychedelics, mental health, and the integrative approach we take to wellness.

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View different platforms and resources that have highlighted our clinic and the life-enhancing work we do.

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Hear from those who are living life to the fullest with help from our individualized ketamine and psychedelic treatments.

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Rapid Relief. Lasting Results.

No matter where you are in your chronic pain or mental health journey, you are not alone. We're here to walk with you every step of the way, helping you achieve and maintain wellness.